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Sober Curious — Ask Us Anything (Yes, Even That)

Split-screen illustration of a liver showing the contrasting effects of healthy food and alcohol. The left side is warm and bright, surrounded by fruit and molecular structures; the right side is dark and cool, with beer, wine, and molecular structures. A large illuminated switch labeled “ON” sits in the center of the liver. Text reads: “Alcohol and Diabetes: How Alcohol Flips the Switch on Your Blood Sugar.” The Bye, Bye Booze logo appears in the upper-right corner.

Alcohol and Diabetes: How Alcohol Flips the Switch on Your Blood Sugar

Alcohol and diabetes are more closely linked than most people think. New research shows that alcohol activates the same metabolic …
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A photorealistic depiction of an iceberg in a square format, offering a view both above and below the water’s surface. Above the water, only a small, sharp-edged tip rises from the calm sea, while below the surface, a massive, deep-blue mass of ice—many times larger—becomes visible. A dramatic sky with thick clouds and distant mountain silhouettes in the background. The image symbolically illustrates that the largest part of a problem lies hidden beneath the surface.

Alcoholism Treatment: More Willenbring. Less Jellinek. 

E. M. Jellinek’s model still shapes alcoholism treatment today—even though it’s based on just 98 questionnaires from the most severely …
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A sleeping man with a transparent depiction of his brain; glowing fluid pathways and astrocytes symbolize how the glymphatic system removes metabolic waste from the brain during sleep.

Your Brain Cleans Itself Every Night – Unless You Drink

The glymphatic system is your brain’s nightly garbage truck – and alcohol shuts it down twice over. How this waste-clearance …
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A metal wastebasket in the style of the 1940s is filled with crumpled

Jellinek’s Woman Problem: He Trashed Their Data. It Took Decades to Undo the Damage.

Jellinek excluded women from his study – their data was too “erratic” for him. What he discarded was a distinct …
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Artistic collage accompanying a critical biography of Jellinek

Jellinek: Shoe Historian, Con Man, Banana Researcher, and Founding Father of Addiction Medicine

In the first part of our Jellinek series, we examined the data foundation of the model that shaped addiction treatment …
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A transparent human silhouette with a glowing heart and nerve pathways, positioned between an overturned glass of alcohol and purple electrical impulses symbolizing fluctuating potassium levels.

Potassium and Alcohol: Why Your Levels Go Haywire — and Why It Matters

Alcohol robs your body of potassium — through multiple pathways at once. That can trigger heart arrhythmias, make withdrawal more …
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An ironic depiction of a female scientist in a white lab coat surrounded by countless glasses of red wine and beer. The liver, pancreas, and skeleton satirize the absurd notion of consuming health-promoting plant compounds through massive amounts of alcohol.

Red Wine as Medicine — You’d Only Need 263 Glasses a Day

Bernd Guzek, MD Physician & Science Journalist The beverage industry has a remarkable talent: it can package a neurotoxin so …
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Two adult women from different generations, shown in a natural three-quarter side view, depicted from the waist up. Their body shapes are realistically and subtly outlined beneath simple, everyday clothing. Calm, dignified editorial photography with a warm sense of intimacy. No sexualized poses, no revealing clothing, no medical or dramatic staging.

Alcohol and Breast Cancer — How Much Drinking Really Raises the Risk

Bernd Guzek, MD/PhD Physician & Science Journalist Breast cancer is the most common cancer in women worldwide. And alcohol is …
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A side view of an overweight man with a pronounced beer belly, humorously depicted as a half-full beer glass with a head of foam. The man is holding a beer mug; the focus is on the symbolic representation of the connection between regular beer consumption and waist circumference.

The Beer Belly: The Problem Has Many Nicknames

Homer Simpson carries one around. It has pet names, its own jokes, and a permanent place in the self-image of …
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Artistic depiction of a crumbling stele. Inscription: Jellinek model showing the types of drinkers he proposed, which have long since been disproved by the NESARC studies.

The Jellinek Model: A Century-Old Theory Built on Shaky Data Falls Apart

E. M. Jellinek shaped decades of addiction treatment with his disease model of alcoholism — based on 98 questionnaires from …
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